Adjudin
Cat. No.：YN360665
CAS No. ：252025-52-8
| 产品名称: | Adjudin |
| CAS No.: | 252025-52-8 |
| Chemical Name: | 1-[(2,4-dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid, hydrazide |
| Synonyms: | AF-2364 |
| 分子量: | 335.19 |
| 分子式: | C₁₅H₁₂Cl₂N₄O |
| SMILES: | O=C(C1=NN(CC2=CC=C(Cl)C=C2Cl)C3=C1C=CC=C3)NN |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Adjudin 是一种广泛研究的男性避孕试剂，具有优越的线粒体抑制作用。 Adjudin 也是一种有效的Cl-通道阻断剂。 |
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Li, K., Ni, Y., He, Y., et al.Inhibition of sperm capacitation and fertilizing capacity by adjudin is mediated by chloride and its channels in humansHum. Repod.28(1),47-59(2013)
Su, L., Cheng, C.Y., and Mruk, D.D.Adjudin-mediated Sertoli-germ cell junction disassembly affects Sertoli cell barrier function in vitro and in vivoInt. J. Biochem. Cell Biol.42(11),1864-1875(2010)
Cheng, C.Y., Silvestrini, B., Grima, J., et al.Two new male contraceptives exert their effects by depleting germ cells prematurely from the testisBiol. Reprod.65(2),449-461(2001)
Xie, Q.R., Liu, Y., Shao, J., et al.Male contraceptive Adjudin is a potential anti-cancer drugBiochem. Pharmacol.85(3),345-355(2013)
