Lintitript
Cat. No.：YN320196
| 产品名称: | Lintitript |
| CAS No.: | 136381-85-6 |
| Chemical Name: | 2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-acetic acid |
| Synonyms: | SR 27897 |
| 分子量: | 411.86 |
| 分子式: | C₂₀H₁₄ClN₃O₃S |
| SMILES: | O=C(O)CN1C(C(NC2=NC(C3=CC=CC=C3Cl)=CS2)=O)=CC4=C1C=CC=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lintitript (SR 27897) 是一种高效，选择性，口服活性，竞争性和非肽类CCK1受体拮抗剂，EC50为 6 nM，Ki为 0.2 nM。Lintitript 对CCK1的选择性比对 CCK2 受体的选择性高 33 倍以上 (EC50值为 200 nM)。Lintitript 增加瘦素的血浆浓度和食物摄入以及胰岛素的血浆浓度。 |
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| Solvent & Solubility: |
Gully, D., Fréhel, D., Marcy, C., et al.Peripheral biological activity of SR 27897: A new potent non-peptide antagonist of CCKA receptorsEur. J. Pharmacol.232(1),13-19(1993)
