Pentagastrin
Cat. No.：YN321362
CAS No. ：5534-95-2
| 产品名称: | Pentagastrin |
| CAS No.: | 5534-95-2 |
| Chemical Name: | N-[(1,1-dimethylethoxy)carbonyl]-β-alanyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide |
| Synonyms: | 五肽胃泌素; ICI-50123 |
| 分子量: | 767.89 |
| 分子式: | C₃₇H₄₉N₇O₉S |
| SMILES: | O=C(N[C@@H](CCSC)C(N[C@@H](CC(O)=O)C(N[C@H](C(N)=O)CC1=CC=CC=C1)=O)=O)[C@@H](NC(CCNC(OC(C)(C)C)=O)=O)CC2=CNC3=C2C=CC=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pentagastrin (ICI-50123) 是胆囊收缩素 B (CCKB) 受体的选择性激动剂，IC50为 11 nM。可增强胃粘膜对酸的防御机制，并保护胃粘膜免受损伤。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Smith, A.J., and Freedman, S.B.CCK-B receptor-mediated stimulation of polyphosphoinositide turnover in GH3 pituitary cells in response to cholecystokinin and pentagastrinLife Sci.58(11),883-895(1996)
Hollande, F., Bali, J.P., and Magous, R.Neurohormonal regulation of histamine synthesis in isolated rabbit fundic mucosal cellsAm. J. Physiol.266(3 Pt. 1),G395-G405(1994)
Botella, A., Delvaux, M., Berry, P., et al.Cholecystokinin and gastrin induce cell contraction in pig ileum by interacting with different receptor subtypesGastroenterology102(3),779-786(1992)
Vagne, M., Collinet, M., Cuber, J.C., et al.Effect of porcine gastrin releasing peptide on gastric secretion and motility and the release of hormonal peptides in conscious cats.Peptides8(3),423-430(1987)
