DC-05
Cat. No.:YN310184
产品名称: | DC-05 |
CAS No.: | 890643-16-0 |
Chemical Name: | α-[[[2-(1H-indol-3-yl)ethyl]amino]methyl]-9H-carbazole-9-ethanol |
Synonyms: | DC-05 |
分子量: | 383.49 |
分子式: | C₂₅H₂₅N₃O |
SMILES: | OC(CNCCC1=CNC2=C1C=CC=C2)CN(C3=CC=CC=C34)C5=C4C=CC=C5 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | DC-05 是一种DNMT1抑制剂,IC50和Kd值分别为 10.3 μM 和 1.09 μM。 |
IC50和靶点: | [{name:"DNMT1:1.09 μM (Kd)"},{name: "DNMT1:10.3 μM (IC50)"},{name: "PRMT1:37.1 μM (IC50)"}] |
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Solvent & Solubility: |
Chen, S., Wang, Y., Zhou, W., et al.Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screeningJ. Med. Chem.57(21),9028-9041(2014)