AZD-7648
Cat. No.：YN420080
CAS No. ：2230820-11-6
规格
价格(RMB)
库存
| 产品名称: | AZD-7648 |
| CAS No.: | 2230820-11-6 |
| Chemical Name: | 7,9-dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one |
| Synonyms: | AZD7648;AZD-7648;97A09L5JCK;7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one;7-Methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-9-(tetrahydro-2H-pyran-4-yl)-7H-purin-8(9H) |
| 分子量: | 380.40 |
| 分子式: | C₁₈H₂₀N₈O₂ |
| SMILES: | CC1=CC2=NC=NN2C=C1NC3=NC=C(N(C)C(N4C5CCOCC5)=O)C4=N3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AZD-7648 是一种有效的选择性DNA-PK抑制剂，具有抗肿瘤活性。 |
| IC50和靶点: | [{name:"DNA-PKcs:91.3 nM (IC50)"},{name: "PI3Kγ:1.37 μM (IC50)"},{name: "ATM:17.93 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Finlay, M., and Verschoyle, R.Amino-triazolopyridine compounds and their use in treating cancer,(2018)
