Samotolisib
Cat. No.：YN420132
CAS No. ：1386874-06-1
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| 产品名称: | Samotolisib |
| CAS No.: | 1386874-06-1 |
| Chemical Name: | |
| Synonyms: | LY3023414 |
| 分子量: | 406.48 |
| 分子式: | C₂₃H₂₆N₄O₃ |
| SMILES: | O=C(N1C[C@@H](OC)C)N(C)C2=C1C3=CC(C4=CC(C(C)(O)C)=CN=C4)=CC=C3N=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Samotolisib (LY3023414) 有效且选择性地抑制PI3Kα，PI3Kβ，PI3Kδ，PI3Kγ，DNA-PK，和mTOR，IC50分别为 6.07 nM，77.6 nM，38 nM，23.8 nM，4.24 nM，和 165 nM。在低纳摩尔浓度下，Samotolisib 有效抑制mTORC1/2。 |
| IC50和靶点: | [{name:"PI3Kα:6.07 nM (IC50)"},{name: "PI3Kγ:23.8 nM (IC50)"},{name: "PI3Kδ:38 nM (IC50)"},{name: "PI3Kβ:77.6 nM (IC50)"},{name: "DNA-PK:4.24 nM (IC50)"},{name: "mTOR:165 nM (IC50)'}, 'mTORC1', 'mTORC2'] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
