Carmustine
Cat. No.:YN290266
CAS No. :154-93-8
产品名称: | Carmustine |
CAS No.: | 154-93-8 |
Chemical Name: | N,N'-bis(2-chloroethyl)-N-nitroso-urea |
Synonyms: | 卡莫司汀 |
分子量: | 214.05 |
分子式: | C₅H₉Cl₂N₃O₂ |
SMILES: | O=C(NCCCl)N(CCCl)N=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Carmustine 是一种抗肿瘤化疗剂,为DNA和RNA的烷化剂 (alkylator)。 |
IC50和靶点: | |
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Wasserman, T.H., Slavik, M., and Carter, S.K.Clinical comparison of the nitrosoureasCancer36(4),1258-1268(1975)
Soma, M.R., Baetta, R., De Renzis, M.R., et al.In vivo enhanced antitumor activity of carmustine [N,N'-bis(2-chloroethyl)-N-nitrosourea] by simvastatinCancer Res.55(3),597-602(1995)
Hayes, C.D., Dey, D., Palavicini, J.P., et al.Striking reduction of amyloid plaque burden in an Alzheimer's mouse model after chronic administration of carmustineBMC Med.11,81(2013)