Pipobroman
Cat. No.:YN290391
产品名称: | Pipobroman |
CAS No.: | 54-91-1 |
Chemical Name: | 1,1'-(1,4-Piperazinediyl)bis[3-bromo-1-propanone]; |
Synonyms: | 哌泊溴烷 |
分子量: | 356.05 |
分子式: | C₁₀H₁₆Br₂N₂O₂ |
SMILES: | O=C(N1CCN(C(CCBr)=O)CC1)CCBr |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Pipobroman 是哌嗪的溴化衍生物,是一种有效的烷基化剂 (alkylating agent)。Pipobroman 通过抑制 DNA 和 RNA 聚合酶或减少嘧啶核苷酸掺入 DNA 发挥其作用。Pipobroman 可用于癌症研究,包括真性红细胞增多症、骨髓增生性肿瘤、AML 等。 |
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Kiladjian, J., et al.: Hemat. J., 4, 198 (2013)
Passamonti, F. & Lazzarino, M.: Leukemia Lymphoma, 44, 1483 (2003)