Altretamine
Cat. No.：YN290501
| 产品名称: | Altretamine |
| CAS No.: | 645-05-6 |
| Chemical Name: | N2,N2,N4,N4,N6,N6-hexamethyl-1,3,5-triazine-2,4,6-triamine |
| Synonyms: | 六甲蜜胺; ENT-50852; RB-1515; WR-95704 |
| 分子量: | 210.28 |
| 分子式: | C₉H₁₈N₆ |
| SMILES: | CN(C)C1=NC(N(C)C)=NC(N(C)C)=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Altretamine 是一种烷化剂 (alkylator)，具有抗肿瘤活性。 |
| IC50和靶点: | |
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Langdon, S.P., Simmonds, R.J., and Stevens, M.F.G.Triazines and related products. Part 26. Synthesis and chemistry of bicyclic analogues of the antitumour drug 2,4,6-tris(dimethylamino)-1,3,5-triazine (hexamethylmelamine)J. Chem. Soc. Perkin 1,993-998(1984)
D'Incalci, M., Erba, E., Balconi, G., et al.Time dependence of the in vitro cytotoxicity of hexamethylmelamine and its metabolitesBr. J. Cancer41(4),630-635(1980)
Miller, K.J., McGovern, R.M., and Ames, M.M.Effect of a hepatic activation system on the antiproliferative activity of hexamethylmelamine against human tumor cell linesCancer Chemother. Pharmacol.15(1),49-53(1985)
Woo, J.H., Shimoni, Y., Yang, W.S., et al.Elucidating compound mechanism of action by network perturbation analysisCell162(2),441-451(2015)
LaBrecque, G.C., Fye, R.L., DeMilo, A.B., et al.Substituted melamines as chemosterilants of house fliesJ. Econ. Entomol.61(6),1621-1632(1968)
