Mirk-IN-1
Cat. No.：YN440225
CAS No. ：1386979-55-0
规格
价格(RMB)
库存
| 产品名称: | Mirk-IN-1 |
| CAS No.: | 1386979-55-0 |
| Chemical Name: | N-[2-Chloro-5-[[[(3-chlorophenyl)methyl]amino]carbonyl]phenyl]-7,8-dihydro-2-methoxy-7-oxo-pyrido[2,3-d]pyrimidine-6-carboxamide; |
| Synonyms: | Dyrk1B/A-IN-1 |
| 分子量: | 498.32 |
| 分子式: | C₂₃H₁₇Cl₂N₅O₄ |
| SMILES: | ClC1=CC=C(C(NCC2=CC(Cl)=CC=C2)=O)C=C1NC(C3=CC4=CN=C(OC)N=C4N=C3O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mirk-IN-1(Dyrk1B/A-IN-1)是Dyrk1B和Dyrk1A高效选择性抑制剂，IC50值分别为68和22nM。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
(1) Ewton, D., et al.: Mol. Cancer Ther., 10, 2104 (2011) & (2) Anderson, K., et al.: Bioorg. Med. Chem. Lett., 23, 6610 (2013)
