LDN-192960 hydrochloride
Cat. No.:YN440272
产品名称: | LDN-192960 hydrochloride |
CAS No.: | 2309172-48-1 |
Chemical Name: | 3-[(2,7-dimethoxy-9-acridinyl)thio]-1-propanamine, dihydrochloride |
Synonyms: | LDN 192960 |
分子量: | 401.35 |
分子式: | C₁₈H₂₂Cl₂N₂O₂S |
SMILES: | NCCCSC1=C(C=C(OC)C=C2)C2=NC3=CC=C(OC)C=C31.Cl.Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | LDN-192960 hydrochloride 是Haspin和DYRK2的双重抑制剂,IC50值分别为 10 nM 和 48 nM。 |
IC50和靶点: | |
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Solvent & Solubility: |
Cuny, G.D., Robin, M., Ulyanova, N.P., et al.Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitorsBioorg. Med. Chem. Lett.20(12),3491-3493(2010)