NSC632839
Cat. No.：YN290014
CAS No. ：157654-67-6
| 产品名称: | NSC632839 |
| CAS No.: | 157654-67-6 |
| Chemical Name: | 3,5-bis[(4-methylphenyl)methylene]-4-piperidinone, monohydrochloride |
| Synonyms: | F6,Ubiquitin Isopeptidase Inhibitor II |
| 分子量: | 339.86 |
| 分子式: | C₂₁H₂₂ClNO |
| SMILES: | O=C1/C(CNC/C1=C\C2=CC=C(C)C=C2)=C/C3=CC=C(C)C=C3.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NSC632839 是一种非选择性肽酶抑制剂，抑制USP2，USP7和SENP2，EC50分别为 45±4 μM，37±1 μM 和 9.8±1.8 μM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Nicholson, B., Leach, C.A., Goldenberg, S.J., et al.Characterization of ubiquitin and ubiquitin-like-protein isopeptidase activitiesProtein Sci.17(6),1035-1043(2008)
Aleo, E., Henderson, C.J., Fontanini, A., et al.Identification of new compounds that trigger apoptosome-independent caspase activation and apoptosisCancer Res.66(18),9235-9244(2006)
