MF-094
Cat. No.：YN290131
CAS No. ：2241025-68-1
| 产品名称: | MF-094 |
| CAS No.: | 2241025-68-1 |
| Chemical Name: | αS-[(cyclohexylcarbonyl)amino]-N-[5-[[(1,1-dimethylethyl)amino]sulfonyl]-1-naphthalenyl]-benzenepropanamide |
| Synonyms: | MF094 |
| 分子量: | 535.70 |
| 分子式: | C₃₀H₃₇N₃O₄S |
| SMILES: | O=C(NC1=CC=CC2=C1C=CC=C2S(=O)(NC(C)(C)C)=O)[C@@H](NC(C3CCCCC3)=O)CC4=CC=CC=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MF-094 是有效，选择性的USP30抑制剂，IC50为120 nM。MF-094 增加蛋白质泛素化，加速有丝分裂。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Kluge, A.F., Lagu, B.R., Maiti, P., et al.Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagyBioorg. Med. Chem. Lett.28(15),2655-2659(2018)
Zhang, X., Han, Y., Liu, S., et al.MF‑094 nanodelivery inhibits oral squamous cell carcinoma by targeting USP30Cell. Mol. Biol. Lett.27(1),107(2022)
