C527
Cat. No.：YN290235
CAS No. ：192718-06-2
| 产品名称: | C527 |
| CAS No.: | 192718-06-2 |
| Chemical Name: | 2-(4-fluorophenyl)-naphth[2,3-d]oxazole-4,9-dione |
| Synonyms: | |
| 分子量: | 293.25 |
| 分子式: | C₁₇H₈FNO₃ |
| SMILES: | O=C1C2=C(N=C(C3=CC=C(F)C=C3)O2)C(C4=CC=CC=C41)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | C527是泛DUB酶的抑制剂，对USP1/UAF1复合物活性较高，IC50值为0.88 μM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Mistry, H., Hsieh, G., Buhrlage, S.J., et al.Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cellsMol. Cancer Ther.12(12),2651-2662(2013)
Brandy, Y., Ononiwu, I., Adedeji, D., et al.Synthesis and cytotoxic activities of some 2-arylnaphtho[2,3-d]oxazole-4,9-dione derivatives on androgen-dependent (LNCaP) and androgen-independent (PC3) human prostate cancer cell linesInvest New Drugs30(4),1709-1714(2012)
