USP7/USP47 inhibitor
Cat. No.:YN290257
产品名称: | USP7/USP47 inhibitor |
CAS No.: | 1247825-37-1 |
Chemical Name: | 4-cyano-5-[(3,5-dichloro-4-pyridinyl)thio]-N-[4-(methylsulfonyl)phenyl]-2-thiophenecarboxamide |
Synonyms: | USP7/47 inhibitor-1 |
分子量: | 484.40 |
分子式: | C₁₈H₁₁Cl₂N₃O₃S₃ |
SMILES: | ClC1=CN=CC(Cl)=C1SC2=C(C#N)C=C(C(NC3=CC=C(S(C)(=O)=O)C=C3)=O)S2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | USP7/USP47 inhibitor 是一种选择性的泛素蛋白特异性蛋白酶 7/47 (USP7/USP47) 抑制剂,EC50值分别为 0.42 μM 和 1.0 μM。 |
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Weinstock, J., Wu, J., Cao, P., et al.Selective dual inhibitors of the cancer-related deubiquitylating proteases USP7 and USP47ACS Med. Chem. Lett.3,789-792(2012)