SJB2-043
Cat. No.:YN290368
CAS No. :63388-44-3
产品名称: | SJB2-043 |
CAS No.: | 63388-44-3 |
Chemical Name: | 2-phenyl-naphth[2,3-d]oxazole-4,9-dione |
Synonyms: | 2-苯基萘并[2,3-D]恶唑-4,9-二酮 |
分子量: | 275.26 |
分子式: | C₁₇H₉NO₃ |
SMILES: | O=C1C2=C(N=C(C3=CC=CC=C3)O2)C(C4=CC=CC=C41)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | SJB2-043 抑制USP1/UAF1复合体,IC50为 544 nM。 |
IC50和靶点: | |
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Mistry, H., Hsieh, G., Buhrlage, S.J., et al.Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cellsMol. Cancer Ther.12(12),2651-2662(2013)
Cho, C.-C., Li, S.G., Lalonde, T.J., et al.Drug repurposing for the SARS-CoV-2 papain-like proteaseChemMedChem17(1),e202100455(2022)