ML-323
Cat. No.：YN290421
CAS No. ：1572414-83-5
| 产品名称: | ML-323 |
| CAS No.: | 1572414-83-5 |
| Chemical Name: | 5-methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-4-pyrimidinamine |
| Synonyms: | ML323 |
| 分子量: | 384.48 |
| 分子式: | C₂₃H₂₄N₆ |
| SMILES: | CC1=CN=C(C2=C(C(C)C)C=CC=C2)N=C1NCC3=CC=C(N4N=NC=C4)C=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ML-323 是一种有效的可逆的USP1-UAF1抑制剂，在Ub-Rho实验中，IC50为 76 nM。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Kennedy, R.D., and D'Andrea, A.D.The Fanconi Anemia/BRCA pathway: New faces in the crowdGenes Dev.19(24),2925-2940(2005)
Liang, Q., Dexheimer, T.S., Zhang, P., et al.A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responsesNat. Chem. Biol.10(4),298-304(2014)
