GBR 12783 dihydrochloride
Cat. No.:YN1730005
产品名称: | GBR 12783 dihydrochloride |
CAS No.: | 67469-75-4 |
Chemical Name: | |
Synonyms: | GBR12783 2HCl |
分子量: | 485.49 |
分子式: | C₂₈H₃₄Cl₂N₂O |
SMILES: | N1(CCOC(C2=CC=CC=C2)C3=CC=CC=C3)CCN(C/C=C/C4=CC=CC=C4)CC1.Cl.Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | GBR 12783 dihydrochloride 是一种特异性,有效且选择性的多巴胺摄取抑制剂,可抑制大鼠和小鼠纹状体突触小体对 [3H] 多巴胺 ([3H]dopamine) 的摄取,IC50分别为 1.8 nM 和 1.2 nM。GBR 12783 dihydrochloride 还可改善大鼠记忆力并增加海马通路乙酰胆碱的释放。 |
IC50和靶点: | |
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Clinical Trial: | |
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