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NMI 8739

Cat. No.:YN1730013

  • CAS No. :129024-87-9

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    • 产品名称: NMI 8739
      CAS No.: 129024-87-9
      Chemical Name: N-[2-(3,4-dihydroxyphenyl)ethyl]-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenamide
      Synonyms:n-docosahexaenoyl dopamine
      分子量:463.65
      分子式:C₃₀H₄₁NO₃
      SMILES:CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(NCCC1=CC=C(O)C(O)=C1)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: NMI 8739 是多巴胺 D2自受体(dopamine D2autoreceptor)的激动剂,是 DHA 载体和神经传递素多巴胺的胺结合物。
      IC50和靶点:
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      In Vivo:
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    • Shashoua, V.E., and Hesse, G.W.N-Docosahexaenoyl, 3-hydroxytyramine: A dopaminergic compound that penetrates the blood-brain barrier and suppresses appetiteLife Sci.58(16),1347-1357(1996)

      Wang, Y., Plastina, P., Vincken, J.-P., et al.N-docosahexaenoyl dopamine, an endocannabinoid-like conjugate of dopamine and the n-3 fatty acid docosahexaenoic acid, attenuates lipopolysaccharide-induced activation of microglia and macrophages via COX-2ACS Chem. Neurosci.Epub ahead of print,(2016)

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