A-381393
Cat. No.：YN1730041
CAS No. ：726174-00-1
| 产品名称: | A-381393 |
| CAS No.: | 726174-00-1 |
| Chemical Name: | |
| Synonyms: | 1H-Benzimidazole, 2-[[4-(3,4-dimethylphenyl)-1-piperazinyl]methyl]-;A-381393 |
| 分子量: | 320.43 |
| 分子式: | C₂₀H₂₄N₄ |
| SMILES: | CC1=CC=C(C=C1C)N2CCN(CC2)CC3=NC4=CC=CC=C4N3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | A-381393 是一种有效、选择性、可透过血脑屏障的dopamine D4receptor拮抗剂，对人 dopamine D4.4，D4.2和 D4.7受体的Ki值分别为 1.5，1.9 和 1.6 nM，选择性是对 D1，D2，D3，D5多巴胺受体的 2700 多倍。A-381393 对 5-HT2A的选择性适中，Ki值为 370 nM。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
