(Rac)-Tavapadon
Cat. No.：YN1730042
CAS No. ：1643462-64-9
| 产品名称: | (Rac)-Tavapadon |
| CAS No.: | 1643462-64-9 |
| Chemical Name: | |
| Synonyms: | (Rac)-PF-06649751; (Rac)-CVL-751 |
| 分子量: | 391.34 |
| 分子式: | C₁₉H₁₆F₃N₃O₃ |
| SMILES: | O=C1NC(C(C)=C(C2=CC=C(OC3=NC=CC=C3C(F)(F)F)C=C2C)N1C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (Rac)-Tavapadon ((Rac)-PF-06649751) 是有效的，选择性非儿茶酚多巴胺 D1 受体 (dopamine D1 receptor) 激动剂。(Rac)-Tavapadon 在 GS 激活试验中显示出强大的完全激动作用，在 β-arrestin2 募集试验中显示出部分激动作用 (GS-cAMP, EC50=0.8 nM; β-arrestin2, EC50=68 nM)。(Rac)-Tavapadon 具有抗帕金森病活性。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
