L-745870
Cat. No.：YN1730063
CAS No. ：158985-00-3
| 产品名称: | L-745870 |
| CAS No.: | 158985-00-3 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 326.82 |
| 分子式: | C₁₈H₁₉ClN₄ |
| SMILES: | ClC(C=C1)=CC=C1N(CC2)CCN2CC3=CNC4=NC=CC=C43 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | L-745870 是一种有效的，选择性的可透过血脑屏障和具有口服活性的多巴胺D4受体拮抗剂，Ki为 0.43 nM，而对 D2(Ki为 960 nM) 和 D3(Ki为 2300 nM) 受体的亲和力相对较弱，对 5-HT2受体，sigma 位点和 α-肾上腺素受体表现出中等亲和力。 |
| IC50和靶点: | [{name:"Human D4 Receptor:4.3 nM (Ki)"},{name: "D2 Receptor:960 nM (Ki)"},{name: "D3 Receptor:2300 nM (Ki)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
