Haloperidol
Cat. No.：YN1730068
| 产品名称: | Haloperidol |
| CAS No.: | 52-86-8 |
| Chemical Name: | 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone |
| Synonyms: | 氟哌啶醇 |
| 分子量: | 375.86 |
| 分子式: | C₂₁H₂₃ClFNO₂ |
| SMILES: | ClC(C=C1)=CC=C1C2(O)CCN(CCCC(C3=CC=C(F)C=C3)=O)CC2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Haloperidol 是有效的dopamine D2 receptor拮抗剂，为一种安定药。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Burstein, E.S., Ma, J., Wong, S., et al.Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: Identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonistJ. Pharmacol. Exp. Ther.315(3),1278-1287(2005)
Richelson, E., and Souder, T.Binding of antipsychotic drugs to human brain receptors: Focus on newer generation compoundsLife Sci.68(1),29-39(2000)
Creese, I., Burt, D.R., and Snyder, S.H.Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugsJ. Neuropsychiatry Clin. Neurosci.8(2),223-226(1996)
Swerdlow, N.R., and Geyer, M.A.Clozapine and haloperidol in an animal model of sensorimotor gating deficits in schizophreniaPharmacol. Biochem. Behav.44(3),741-744(1993)
