Amisulpride
Cat. No.：YN1730072
| 产品名称: | Amisulpride |
| CAS No.: | 71675-85-9 |
| Chemical Name: | 4-amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxy-benzamide |
| Synonyms: | 氨磺必利; DAN 2163 |
| 分子量: | 369.48 |
| 分子式: | C₁₇H₂₇N₃O₄S |
| SMILES: | CCN1C(CNC(C2=CC(S(=O)(CC)=O)=C(N)C=C2OC)=O)CCC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Amisulpride 是一种多巴胺D2/D3受体拮抗剂，对于人多巴胺D2和D3的Ki值分别为 2.8 和 3.2 nM。 |
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Abbas, A.I., Hedlund, P.B., Huang, X.P., et al.Amisulpride is a potent 5-HT7 antagonist: Relevance for antidepressant actions in vivoPsychopharmacology (Berl.)205(1),119-128(2009)
Schoemaker, H., Claustre, Y., Fage, D., et al.Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivityJ. Pharmacol. Exp. Ther.280(1),83-97(1997)
Papp, M., and Wieronska, J.Antidepressant-like activity of amisulpride in two animal models of depressionJ. Psychopharmacol.14(1),46-52(2000)
