Zuclopenthixol
Cat. No.：YN1730093
| 产品名称: | Zuclopenthixol |
| CAS No.: | 53772-83-1 |
| Chemical Name: | 4-[(3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]-1-piperazineethanol |
| Synonyms: | (Z)-Clopenthixol |
| 分子量: | 400.96 |
| 分子式: | C₂₂H₂₅ClN₂OS |
| SMILES: | OCCN1CCN(CC/C=C2C3=C(SC4=C\2C=CC=C4)C=CC(Cl)=C3)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Zuclopenthixol 是一种噻吨衍生物，它是多巴胺D1/D2受体 (dopamine D1/D2 receptor) 的拮抗剂。 |
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Hajjo, R., Setola, V., Roth, B.L., et al.Chemocentric informatics approach to drug discovery: Identification and experimental validation of selective estrogen receptor modulators as ligands of 5-hydroxytryptamine-6 receptors and as potential cognition enhancersJ. Med. Chem.55(12),5704–5719(2012)
Christensen, A.V., Arnt, J., Hyttel, J., et al.Pharmacological effects of a specific dopamine D-1 antagonist SCH 23390 in comparison with neurolepticsLife Sci.34(16),1529-1540(1984)
Khalifa, A.E.Zuclopenthixol facilitates memory retrieval in rats: Possible involvement of noradrenergic and serotonergic mechanismsPharmacol. Biochem. Behav.75(4),755-762(2003)
