Pramipexole dihydrochloride hydrate
Cat. No.:YN1730096
产品名称: | Pramipexole dihydrochloride hydrate |
CAS No.: | 191217-81-9 |
Chemical Name: | |
Synonyms: | Pramipexole 2HCl Monohydrate,普拉克索盐酸盐水合物,Mirapex,普拉克索 |
分子量: | 302.26 |
分子式: | C₁₀H₂₁Cl₂N₃OS |
SMILES: | [H]Cl.NC1=NC(CC[C@H](NCCC)C2)=C2S1.[H]Cl.O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Pramipexole dihydrochloride hydrate 是一种选择性的 D2 型多巴胺受体 (dopamine receptor) 激动剂,对 D2 型受体、D2、D3、D4亚型受体的Ki值分别为 2.2 nM、3.9 nM、0.5 nM、1.3 nM。 Pramipexole dihydrochloride hydrate 可用于帕金森综合症和腿多动综合征的研究。Pramipexole dihydrochloride hydrate 可以透过血脑屏障。 |
IC50和靶点: | [{name:"D2 Receptor:3.9 nM (Ki)"},{name: "D3 Receptor:0.5 nM (Ki)"},{name: "D4 Receptor:1.3 nM (Ki)"}] |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |