Ropinirole hydrochloride
Cat. No.：YN1730098
CAS No. ：91374-20-8
| 产品名称: | Ropinirole hydrochloride |
| CAS No.: | 91374-20-8 |
| Chemical Name: | 4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one, monohydrochloride |
| Synonyms: | 盐酸罗匹尼罗; SKF 101468 hydrochloride |
| 分子量: | 296.84 |
| 分子式: | C₁₆H₂₅ClN₂O |
| SMILES: | O=C1NC2=C(C(CCN(CCC)CCC)=CC=C2)C1.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ropinirole hydrochloride 是一种有效的D3/D2受体激动剂，对 D2受体的Ki为 29 nM。Ropinirole hydrochloride 对 hD2，hD3和 hD4受体的pEC50分别为 7.4、8.4 和 6.8。Ropinirole hydrochloride 对 D1受体没有亲和力。Ropinirole hydrochloride 具有用于帕金森氏病潜力。 |
| IC50和靶点: | [{name:"D2 Receptor:29 nM (Ki)"},{name: "hD2 Receptor:7.4 (pEC50)"},{name: "hD3 Receptor:8.4 (pEC50)"},{name: "hD4.4 Receptor:6.8 (pEC50)"}] |
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Eden, R.J., Costall, B., Domeney, A.M., et al.Preclinical pharmacology of ropinirole (SK&F 101468-A) a novel dopamine D2 agonistPharmacol. Biochem. Behav.38(1),147-154(1991)
