Sulpiride
Cat. No.：YN1730100
| 产品名称: | Sulpiride |
| CAS No.: | 15676-16-1 |
| Chemical Name: | 5-(aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-benzamide |
| Synonyms: | 舒必利 |
| 分子量: | 341.43 |
| 分子式: | C₁₅H₂₃N₃O₄S |
| SMILES: | O=C(NCC1N(CC)CCC1)C2=CC(S(=O)(N)=O)=CC=C2OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sulpiride 是多巴胺 D2 受体拮抗剂, 是苯甲酰胺类的非典型抗精神病试剂, 主要用于研究与精神分裂症和严重抑郁障碍相关的精神病, 有时使用低剂量研究焦虑和轻度抑郁症。 |
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Toll, L., Berzetei-Gurske, I.P., Polgar, W.E., et al.Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medicationsNIDA Res. Monogr.178,440-466(1998)
Pezze, M.A., Dalley, J.W., and Robbins, T.W.Remediation of attentional dysfunction in rats with lesions of the medial prefrontal cortex by intra-accumbens administration of the dopamine D2/3 receptor antagonist sulpiridePsychopharmacology (Berl.)202(1-3),307-313(2009)
Dong, E., Nelson, M., Grayson, D.R., et al.Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylationProc. Natl. Acad. Sci. USA105(36),13614-13619(2008)
