Propionylpromazine hydrochloride
Cat. No.：YN1730124
| 产品名称: | Propionylpromazine hydrochloride |
| CAS No.: | 7681-67-6 |
| Chemical Name: | 1-[10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-yl]-1-propanone, monohydrochloride |
| Synonyms: | Propiopromazine hydrochloride |
| 分子量: | 376.94 |
| 分子式: | C₂₀H₂₅ClN₂OS |
| SMILES: | CCC(C(C=C1N2CCCN(C)C)=CC=C1SC3=C2C=CC=C3)=O.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Propionylpromazine hydrochloride (Propiopromazine hydrochloride) 是一种多巴胺受体 D2 (DRD2) 拮抗剂，可用于帕金森氏病的研究。 |
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Fielding, S., and Lal, H.Biochemical actions of neuroleptic drugs: focus on the dopamine receptorHandbook of psychopharmacology,37-55(1978)
Ejendal, K.F.K., Meyer, J.M., Brust, T.F., et al.Discovery of antagonists of tick dopamine receptors via chemical library screening and comparative pharmacological analysesInsect Biochem. Molec.42(11),846-853(2012)
Meyer, J.M., Ejendal, K.F.K., Avramova, L.V., et al.A "genome-to-lead" approach for insecticide discovery: pharmacological characterization and screening of Aedes aegypti D(1)-like dopamine receptorsPlos Negl. Trop. D.6(1),e1478(2012)
Ejendal, K.F.K., Meyer, J.M., Brust, T.F., et al.Discovery of antagonists of tick dopamine receptors via chemical library screening and comparative pharmacological analysesInsect Biochem. Molec.42(11),846-853(2012)
Chan, C., Yin, H., Garforth, J., et al.Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugsJ. Med. Chem.41(2),148-156(1998)
Ye, X., Linton, J.M., Schork, N.J., et al.A pharmacological network for lifespan extension in Caenorhabditis elegansAging Cell13(2),206-215(2014)
