SB-332235
Cat. No.:YN322446
产品名称: | SB-332235 |
CAS No.: | 276702-15-9 |
Chemical Name: | 6-chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxy-benzenesulfonamide |
Synonyms: | SB332235;SB-332235 |
分子量: | 410.66042 |
分子式: | C13H10Cl3N3O4S |
SMILES: | O=C(NC1=CC=C(C(S(N)(=O)=O)=C1O)Cl)NC2=C(Cl)C(Cl)=CC=C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | SB-332235 是一种高效、口服活性、选择性的非肽CXCR2拮抗剂,IC50为 7.7 nM。SB-332235 对CXCR2的选择性比CXCR1高 285 倍。SB-332235 对家兔急性和慢性关节炎模型的抑制作用。SB-332235 抑制 AML 细胞活性。 |
IC50和靶点: | |
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