Biacetyl monoxime
Cat. No.：YN300102
| 产品名称: | Biacetyl monoxime |
| CAS No.: | 57-71-6 |
| Chemical Name: | 2,3-butanedione, 2-oxime |
| Synonyms: | Diacetyl monoxime; DAM |
| 分子量: | 101.1 |
| 分子式: | C4H7NO2 |
| SMILES: | CC(/C(C)=N/O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Biacetyl monoxime (Diacetyl monoxime) 是一种肌球蛋白 ATP 酶 (myosinATPase) 抑制剂，是一种骨骼肌和心肌收缩抑制剂。Biacetyl monoxime 也是一种特征良好的骨骼肌肌球蛋白 II（myosin-II）的化学和运动活性的非竞争性抑制剂。Biacetyl monoxime 诱导肌质网 Ca2+释放。 |
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Sellin, L.C., and McArdle, J.J.Multiple effects of 2,3-butanedione monoximePharmacol. Toxicol.74(6),305-313(1994)
Ostap, E.M.2,3-Butanedione monoxime (BDM) as a myosin inhibitorJ. Muscle Res. Cell Motil.23(4),305-308(2002)
Eisfeld, J., Mikala, G., Varadi, G., et al.Inhibition of cloned human L-type cardiac calcium channels by 2,3-butanedione monoxime does not require PKA-dependent phosphorylation sitesBiochem. Biophys. Res. Commun.230(3),489-492(1997)
Adhikari, B.B., and Wang, K.Interplay of troponin- and myosin-based pathways of calcium activation in skeletal and cardiac muscle: The use of W7 as an inhibitor of thin filament activationBiophys. J.86(1),359-370(2004)
