Pomalidomide-amido-C1-Br
Cat. No.:YN430172
产品名称: | Pomalidomide-amido-C1-Br |
CAS No.: | 2351106-38-0 |
Chemical Name: | |
Synonyms: | |
分子量: | 394.18 |
分子式: | C₁₅H₁₂BrN₃O₅ |
SMILES: | O=C(NC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CBr |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Pomalidomide-amido-C1-Br 是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 Pomalidomide 的 cereblon 配体和 1 个 linker。Pomalidomide-amido-C1-Br 可通过 PROTAC 技术合成 B-Raf 降解剂 PROTAC B-Raf degrader 1 (HY-111758)。PROTAC B-Raf degrader 1 具有抗肿瘤活性。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |