Pluripotin
Cat. No.：YN350047
CAS No. ：839707-37-8
| 产品名称: | Pluripotin |
| CAS No.: | 839707-37-8 |
| Chemical Name: | N-(3-(7-(1,3-dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide |
| Synonyms: | SC1 |
| 分子量: | 550.54 |
| 分子式: | C₂₇H₂₅F₃N₈O₂ |
| SMILES: | CN1C(NC2=NC=C3C(N(C)C(N(C4=CC(NC(C5=CC=CC(C(F)(F)F)=C5)=O)=CC=C4C)C3)=O)=N2)=CC(C)=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pluripotin 是ERK1和RasGAP的双重抑制剂，KD分别为 98 nM 和 212 nM。Pluripotin 还抑制RSK1，RSK2，RSK3和RSK4，IC50分别为 0.5，2.5，3.3 和 10.0 μM。 |
| IC50和靶点: | [{name:"ERK1:98 nM (Kd)"},{name: "RasGAP:212 nM (Kd)"},{name: "RSK1:0.5 μM (IC50)"},{name: "RSK2:2.5 μM (IC50)"},{name: "RSK3:3.3 μM (IC50)"},{name: "RSK4:10 μM (IC50)"}] |
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| Solvent & Solubility: |
Chen, S., Do, J.T., Zhang, Q., et al.Self-renewal of embryonic stem cells by a small moleculeProc. Natl. Acad. Sci. USA103(46),17266-17271(2006)
