Urolithin B
Cat. No.：YN350117
CAS No. ：1139-83-9
| 产品名称: | Urolithin B |
| CAS No.: | 1139-83-9 |
| Chemical Name: | 3-hydroxy-6H-dibenzo[b,d]pyran-6-one |
| Synonyms: | 尿石素B |
| 分子量: | 212.20 |
| 分子式: | C₁₃H₈O₃ |
| SMILES: | O=C1C2=CC=CC=C2C3=CC=C(O)C=C3O1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Urolithin B 是 ellagitannins 的肠道微生物代谢产物之一，具有抗炎和抗氧化作用。Urolithin B 通过降低 IκBα 的磷酸化和降解来抑制NF-κB活性。Urolithin B 抑制JNK、ERK和Akt的磷酸化，增强AMPK的磷酸化。Urolithin B 也是骨骼肌质量的调节因子。 |
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Tomás-Barberán, F.A., González-Sarrías, A., García-Villalba, R., et al.Urolithins, the rescue of "old" metabolites to understand a "new" concept: Metabotypes as a nexus among phenolic metabolism, microbiota dysbiosis, and host health statusMol. Nutr. Food Res.61(1),(2017)
Liu, W., Ma, H., Frost, L., et al.Pomegranate phenolics inhibit formation of advanced glycation endproducts by scavenging reactive carbonyl speciesFood Funct.5(11),2996-3004(2014)
Adams, L.S., Zhang, Y., Seeram, N.P., et al.Pomegranate ellagitannin-derived compounds exhibit antiproliferative and antiaromatase activity in breast cancer cells in vitroCancer Prev. Res. (Phila.)3(1),108-113(2010)
Lee, G., Park, J.-S., Lee, E.-J., et al.Anti-inflammatory and antioxidant mechanisms of urolithin B in activated microgliaPhytomedicine55,50-57(2019)
