Lidocaine
Cat. No.：YN350217
| 产品名称: | Lidocaine |
| CAS No.: | 137-58-6 |
| Chemical Name: | 2-(diethylamino)-N-(2,6-dimethylphenyl)-acetamide |
| Synonyms: | 利多卡因; Lignocaine |
| 分子量: | 234.34 |
| 分子式: | C₁₄H₂₂N₂O |
| SMILES: | O=C(NC1=C(C)C=CC=C1C)CN(CC)CC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lidocaine (Lignocaine) 抑制涉及复杂电压和依赖性的钠通道 (sodium channels)。Lidocaine 通过调节 miR-145 表达和进一步抑制MEK/ERK和NF-κB信号通路来减少胃癌细胞的生长，迁移和侵袭。Lidocaine 是一种酰胺衍生物，有局部麻醉活性。Lidocaine 一种研究室性心律失常的药物和有效的肿瘤抑制剂。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Kumar, M., Chawla, R., and Goyal, M.Topical anesthesiaJ. Anaesthesiol. Clin. Pharmacol.31(4),450-456(2015)
DeCarvalho, T.C., Tosato, F., Souza, L.M., et al.Thin layer chromatography coupled to paper spray ionization mass spectrometry for cocaine and its adulterants analysisForensic Sci. Int.262,56-65(2016)
Floriani, G., Gasparetto, J.C., Pontarolo, R., et al.Development and validation of an HPLC-DAD method for simultaneous determination of cocaine, benzoic acid, benzoylecgonine and the main adulterants found in products based on cocaineForensic Sci. Int.235,32-39(2014)
Grobério, T.S., Zacca, J.J., Botelho, É.D., et al.Discrimination and quantification of cocaine and adulterants in seized drug samples by infrared spectroscopy and PLSRForensic Sci. Int.257,297-306(2015)
Phillips, K.A., Hirsch, G.A., Epstein, D.H., et al.Cardiac complications of unwitting co-injection of quinine/quinidine with heroin in an intravenous drug userJ. Gen. Intern. Med.27(12),1722-1725(2012)
