Pachymic acid
Cat. No.：YN350227
| 产品名称: | Pachymic acid |
| CAS No.: | 29070-92-6 |
| Chemical Name: | 3β-(acetyloxy)-16α-hydroxy-24-methylene-lanost-8-en-21-oic acid |
| Synonyms: | 茯苓酸; 3-O-Acetyltumulosic acid |
| 分子量: | 528.76 |
| 分子式: | C₃₃H₅₂O₅ |
| SMILES: | O[C@@H]([C@]1([H])[C@H](C(O)=O)CCC(C(C)C)=C)C[C@@]([C@]1(C)CC2)(C)C3=C2[C@]4(C)[C@](CC3)([H])C(C)(C)[C@@H](OC(C)=O)CC4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pachymic acid 是一种来自 P. cocos 的三萜类化合物。Pachymic acid 抑制Akt和ERK信号传导途径。 |
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Miao, G., Han, J., Zhang, J., et al.Targeting pyruvate kinase M2 and hexokinase II, pachymic acid impairs glucose metabolism and induces mitochondrial apoptosisBiol. Pharm. Bull.42(1),123-129(2019)
Ling, H., Jia, X., Zhang, Y., et al.Pachymic acid inhibits cell growth and modulates arachidonic acid metabolism in nonsmall cell lung cancer A549 cellsMol. Carcinog.49(3),271-282(2010)
Ma, J., Liu, J., Lu, C., et al.Pachymic acid induces apoptosis via activating ROS-dependent JNK and ER stress pathways in lung cancer cellsCancer Cell Int.15,78(2015)
Jiang, G.-P., Liao, Y.-J., Huang, L.-L., et al.Effects and molecular mechanism of pachymic acid on ferroptosis in renal ischemia reperfusion injuryMol. Med. Rep.23(1),1(2021)
