6-Bnz-cAMP sodium salt
Cat. No.：YN450158
| 产品名称: | 6-Bnz-cAMP sodium salt |
| CAS No.: | 1135306-29-4 |
| Chemical Name: | N-benzoyl-adenosine cyclic 3',5'-(hydrogen phosphate), monosodium salt |
| Synonyms: | |
| 分子量: | 455.294031 |
| 分子式: | C17H15N5O7P • Na |
| SMILES: | O[C@H]1[C@H](N2C=NC3=C2N=CN=C3NC(C4=CC=CC=C4)=O)O[C@@]5([H])[C@@]1([H])OP(OC5)([O-])=O.[Na+] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 6-Bnz-cAMP 钠盐是一种细胞通透性 cAMP 类似物。6-Bnz-cAMP 选择性激活 cAMP 依赖的PKA信号通路，但不激活 Epac 信号通路。 |
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Schwede, F., Maronde, F., Genieser, H., et al.Cyclic nucleotide analogs as biochemical tools and prospective drugsPharmacol. Ther.87(2),199-226(2000)
Christensen, A.E., Selheim, F., de Rooij, J., et al.cAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extensionJ. Biol. Chem.278(37),35394-35402(2003)
Hewer, R.C., Sala-Newby, G.B., Wu, Y.J., et al.PKA and Epac synergistically inhibit smooth muscle cell proliferationJ. Mol. Cell. Cardiol.50(1),87-98(2011)
