SR-3576
Cat. No.:YN350282
产品名称: | SR-3576 |
CAS No.: | 1164153-22-3 |
Chemical Name: | 3-[4-[[[(3-methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide |
Synonyms: | |
分子量: | 501.5 |
分子式: | C27H27N5O5 |
SMILES: | CC1=CC=CC(NC(NC2=CN(C3=CC=CC(C(NC4=CC(OC)=C(OC)C(OC)=C4)=O)=C3)N=C2)=O)=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | SR-3576 是一种高效、选择性的JNK3抑制剂,IC50为7 nM。 |
IC50和靶点: | [{name:"JNK3:7 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Kamenecka, T., Habel, J., Duckett, D., et al.Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38J. Biol. Chem.284(19),12853-12861(2009)