CCT031374 hydrobromide
Cat. No.:YN450161
产品名称: | CCT031374 hydrobromide |
CAS No.: | 1219184-91-4 |
Chemical Name: | 1-[1,1′-biphenyl]-4-yl-2-(2,3-dihydro-9H-imidazo[1,2-a]benzimidazol-9-yl)-ethanone, monohydrobromide |
Synonyms: | CCT031374 hydrobromide |
分子量: | 434.32852 |
分子式: | C23H19N3O • HBr |
SMILES: | O=C(CN1C2=C(N3C1=NCC3)C=CC=C2)C4=CC=C(C5=CC=CC=C5)C=C4.Br |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | CCT 031374 氢溴酸盐是β-catenin/transcription factor (TCF)复合信号传导的有效抑制剂。CCT 031374 抑制Wnt信号通路基因的 TCF 依赖性转录。CCT 031374 具有抗肿瘤活性。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Ewan, K., Pajak, B., Stubbs, M., et al.A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcriptionCancer Res.70(14),5963-5973(2010)