TRULI
Cat. No.：YN450164
CAS No. ：1424635-83-5
| 产品名称: | TRULI |
| CAS No.: | 1424635-83-5 |
| Chemical Name: | N-[3-(phenylmethyl)-2(3H)-thiazolylidene]-1H-pyrrolo[2,3-b]pyridine-3-carboxamide |
| Synonyms: | Lats-IN-1 |
| 分子量: | 334.39612 |
| 分子式: | C18H14N4OS |
| SMILES: | O=C(C1=CNC2=C1C=CC=N2)N=C3SC=CN3CC4=CC=CC=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TRULI (Lats-IN-1) 是一种高效的，ATP 竞争性的Lats1和Lats2激酶抑制剂。TRULI 能促进有丝分裂后哺乳动物组织的Yap依赖性增殖。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Kastan, N., Gnedeva, K., Alisch, T., et al.Small-molecule inhibition of Lats kinases may promote Yap-dependent proliferation in postmitotic mammalian tissuesNat. Commun.12(1),3100(2021)
