p38 MAP Kinase Inhibitor IV
Cat. No.：YN350289
| 产品名称: | p38 MAP Kinase Inhibitor IV |
| CAS No.: | 1638-41-1 |
| Chemical Name: | 3,4,6-trichloro-2-[(2,3,5-trichloro-6-hydroxyphenyl)sulfonyl]-phenol |
| Synonyms: | p38 MAP Kinase Inhibitor IV |
| 分子量: | 456.9 |
| 分子式: | C12H4Cl6O4S |
| SMILES: | ClC1=CC(Cl)=C(C(S(C2=C(C(Cl)=CC(Cl)=C2O)Cl)(=O)=O)=C1O)Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | p38 MAP Kinase Inhibitor IV 是一种高度特异的 ATP 竞争性p38αMAPK抑制剂，p38 MAP Kinase Inhibitor IV 对p38α和p38βMAPK 的IC50分别为 0.13 和 0.55 μM。 |
| IC50和靶点: | [{name:"p38α:0.13 μM (IC50)"},{name: "p38β:0.55 μM (IC50)"},{name: "p38δ:8.63 μM (IC50)"},{name: "p38χ:5.47 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Liu, Y.C., Ko, C.C., Cheng, F.C., et al.Identification of a novel competitive inhibitor of p38α MAPK by a human PBMC screenBiochim. Biophys. Res. Commun.352(3),656-661(2007)
