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Oct4 inducer-1

Cat. No.:YN450168

  • CAS No. :182564-41-6

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    • 参考文献
    • 产品名称: Oct4 inducer-1
      CAS No.: 182564-41-6
      Chemical Name: 4-fluoro-N-1H-indol-5-yl-benzamide
      Synonyms:
      分子量:254.3
      分子式:C15H11FN2O
      SMILES:O=C(NC1=CC=C(NC=C2)C2=C1)C3=CC=C(F)C=C3
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Oct4 inducer-1 (compound OAC-3) 是一种有效的Oct4激活剂。Oct4 inducer-1 激活 Oct4 和 Nanog 启动子,促进诱导多能干细胞 (iPSC) 的形成。Oct4 inducer-1 通过提高效率和缩短重编程时间,促进了细胞的重编程。
      IC50和靶点:
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      In Vivo:
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    • Niwa, H., Miyazaki, J.i., and Smith, A.G.Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cellsNat. Genet.24(4),372-376(2000)

      Takahashi, K., Tanabe, K., Ohnuki, M., et al.Induction of pluripotent stem cells from adult human fibroblasts by defined factorsCell131,861-872(2007)

      Li, W., Tian, E., Chen, Z.X., et al.Identification of Oct4-activating compounds that enhance reprogramming efficiencyProc. Natl. Acad. Sci. USA109(51),20853-20858(2012)

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