Oct4 inducer-1
Cat. No.:YN450168
CAS No. :182564-41-6
产品名称: | Oct4 inducer-1 |
CAS No.: | 182564-41-6 |
Chemical Name: | 4-fluoro-N-1H-indol-5-yl-benzamide |
Synonyms: | |
分子量: | 254.3 |
分子式: | C15H11FN2O |
SMILES: | O=C(NC1=CC=C(NC=C2)C2=C1)C3=CC=C(F)C=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Oct4 inducer-1 (compound OAC-3) 是一种有效的Oct4激活剂。Oct4 inducer-1 激活 Oct4 和 Nanog 启动子,促进诱导多能干细胞 (iPSC) 的形成。Oct4 inducer-1 通过提高效率和缩短重编程时间,促进了细胞的重编程。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Niwa, H., Miyazaki, J.i., and Smith, A.G.Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cellsNat. Genet.24(4),372-376(2000)
Takahashi, K., Tanabe, K., Ohnuki, M., et al.Induction of pluripotent stem cells from adult human fibroblasts by defined factorsCell131,861-872(2007)
Li, W., Tian, E., Chen, Z.X., et al.Identification of Oct4-activating compounds that enhance reprogramming efficiencyProc. Natl. Acad. Sci. USA109(51),20853-20858(2012)