p38 MAPK-IN-4
Cat. No.:YN350295
产品名称: | p38 MAPK-IN-4 |
CAS No.: | 219138-24-6 |
Chemical Name: | 2-(4-chlorophenyl)-4-(4-fluorophenyl)-1,2-dihydro-5-(4-pyridinyl)-3H-pyrazol-3-one |
Synonyms: | |
分子量: | 365.8 |
分子式: | C20H13ClFN3O |
SMILES: | FC1=CC=C(C2=C(C3=CC=NC=C3)NN(C4=CC=C(Cl)C=C4)C2=O)C=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | p38 MAPK-IN-4 (compound 6) 是一种p38 MAPK抑制剂,50为 35 nM。 |
IC50和靶点: | [{name:"p38:35 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
de Laszlo, S.E., Visco, D., Agarwal, L., et al.Pyrroles and other heterocycles as inhibitors of p38 kinaseBioorg. Med. Chem. Lett.8(19),2689-2694(1998)
Zhang, R., Bitler, B.J., and Peterson, J.Methods and compositions for screening modulators of oncogene-induced senescenceUS 14/202,909,1-10(2014)