GA-017
Cat. No.：YN450172
CAS No. ：2351906-74-4
| 产品名称: | GA-017 |
| CAS No.: | 2351906-74-4 |
| Chemical Name: | |
| Synonyms: | (Z)-2-(1-(2,4-dihydroxy-3-methylphenyl)propylidene)-N-(3-hydroxybenzyl)hydrazine-1-carboxamide |
| 分子量: | 343.38 |
| 分子式: | C18H21N3O4 |
| SMILES: | CC\C(=N\NC(=O)NCC1=CC(=CC=C1)O)C2=C(O)C(=C(O)C=C2)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GA-017是一种强效的选择性LATS1和LATS2(大型肿瘤抑制激酶 1/2) 抑制剂，其IC50值分别为 4.10 和 3.92 nM。GA-017 是一种细胞增殖激活剂。GA-017 促进YAP/TAZ激活和核转位。GA-017 在 3D 培养条件下促进细胞生长。GA-017 增强小鼠肠道类器官离体的形成。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
