ASK1-IN-1
Cat. No.：YN350298
CAS No. ：2411382-24-4
| 产品名称: | ASK1-IN-1 |
| CAS No.: | 2411382-24-4 |
| Chemical Name: | 3-methoxy-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]-1-(2-pyrazinyl)-1H-pyrazole-4-carboxamide |
| Synonyms: | |
| 分子量: | 405.41362 |
| 分子式: | C19H19N9O2 |
| SMILES: | O=C(C1=CN(C2=NC=CN=C2)N=C1OC)NC3=CC=CC(C4=NN=CN4C(C)C)=N3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ASK1-IN-1 是一种中枢神经系统渗透剂凋亡信号调节激酶 1 (ASK1) 抑制剂，具有良好的效价 (细胞IC50=138 nM; BiochemicalIC50=21 nM)。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Xin, Z., Himmelbauer, K., Jones, J.H., et al.Discovery of CNS-penetrant apoptosis signal-regulating kinase 1 (ASK1) inhibitorsACS Med. Chem. Lett.11(4),485-490(2020)
