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PROTAC MEK1 Degrader-1

Cat. No.:YN350304

  • CAS No. :548756-68-9

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    • 生物活性
    • 参考文献
    • 产品名称: PROTAC MEK1 Degrader-1
      CAS No.: 548756-68-9
      Chemical Name: N-[5-[3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl]-1,3,4-oxadiazol-2-yl]-4-morpholineethanamine
      Synonyms:
      分子量:545.3
      分子式:C20H19F3IN5O2
      SMILES:FC1=C(NC2=CC=C(I)C=C2F)C(C3=NN=C(NCCN4CCOCC4)O3)=CC=C1F
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: PD-334581 是一种MEK1抑制剂。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Warmus, J.S., Flamme, C., Zhang, L.Y., et al.2-Alkylamino- and alkoxy-substituted 2-amino-1,3,4-oxadiazoles-O-alkyl benzohydroxamate esters replacements retain the desired inhibition and selectivity against MEK (MAP ERK kinase)Bioorg. Med. Chem. Lett.18(23),6171-6174(2008)

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