Withanolide B
Cat. No.：YN350305
| 产品名称: | Withanolide B |
| CAS No.: | 56973-41-2 |
| Chemical Name: | 6α,7α-epoxy-5α,22R-dihydroxy-1-oxo-ergosta-2,24-dien-26-oic acid, δ-lactone |
| Synonyms: | Withanolide B |
| 分子量: | 454.6 |
| 分子式: | C28H38O5 |
| SMILES: | O=C1[C@@]2(C)[C@]([C@@H](O3)[C@@H]3[C@]4([H])[C@]2([H])CC[C@@]5(C)[C@@]4([H])CC[C@@H]5[C@H](C)[C@@]6(OC(C(C)=C(C)C6)=O)[H])(O)CC=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Withanolide B 是W. somnifera Dunal的活性成分。Withanolide B 通过ERK1/2和Wnt/β-catenin信号通路促进 hBMSCs 的成骨分化。 Withanolide B 具有神经保护、抗关节炎、抗衰老和抗癌的作用。 |
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Nayak, P.S., Upadhyaya, S.D., and Upadhyaya, A.HPLC analysis of bioactive steroids from the roots of Withania somnifera (L.) Dunal (Ashwagandha)Lat. Am. J. Pharm.29(3),468-471(2010)
Gorelick, J., Rivka, R., Avinoam, S., et al.Hypoglycemic activity of withanolides and elicitated Withania somniferaPhytochemistry116,283-289(2015)
Kumar, G., Paliwal, P., Patnaik, N., et al.Withania somnifera phytochemicals confer neuroprotection by selective inhibition of nNos: An in silico study to search potent and selective inhibitors for human nNOSJ. Theor. Comput. Chem.16(5),1750042(2017)
Mukherjee, S., Kumar, G., and Patnaik, R.Identification of potential inhibitors of PARP-1, a regulator of caspase-independent cell death pathway, from Withania somnifera phytochemicals for combating neurotoxicity: A structure-based in-silico studyJ. Theor. Comput. Chem.16(7),1750062(2017)
