AEG3482
Cat. No.：YN350308
CAS No. ：63735-71-7
| 产品名称: | AEG3482 |
| CAS No.: | 63735-71-7 |
| Chemical Name: | 6-phenyl-imidazo[2,1-b]-1,3,4-thiadiazole-2-sulfonamide |
| Synonyms: | |
| 分子量: | 280.32828 |
| 分子式: | C10H8N4O2S2 |
| SMILES: | NS(C1=NN2C(S1)=NC(C3=CC=CC=C3)=C2)(=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AEG3482 是一种有效的抗凋亡化合物，可诱导热休克蛋白 70 (HSP70) 的表达来抑制JNK活性。AEG3482 通过直接结合HSP90，从而促进HSP70和 HSP25 的HSF1依赖性表达。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Salehi, A.H., Morris, S.J., Ho, W.C., et al.AEG3482 is an antiapoptotic compound that inhibits Jun kinase activity and cell death through induced expression of heat shock protein 70Chem. Biol.13(2),213-223(2006)
