NMDAR/TRPM4-IN-2 free base
Cat. No.:YN350320
CAS No. :1353979-43-7
产品名称: | NMDAR/TRPM4-IN-2 free base |
CAS No.: | 1353979-43-7 |
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分子量: | 257.175 |
分子式: | C11H17BrN2 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | NMDAR/TRPM4-IN-2 free base (化合物 8) 是一种有效的NMDAR/TRPM4相互作用界面抑制剂。NMDAR/TRPM4-IN-2 free base 具有神经保护活性。NMDAR/TRPM4-IN-2 free base 可预防 NMDA 诱导的海马神经元细胞死亡和线粒体功能障碍,其IC50值为 2.1 μM。NMDAR/TRPM4-IN-2 free base 保护小鼠免受 MCAO 诱导的脑损伤和 NMDA 诱导的视网膜神经节细胞丢失。 |
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