PROTAC BRAF-V600E degrader-1
Cat. No.：YN350341
| 产品名称: | PROTAC BRAF-V600E degrader-1 |
| CAS No.: | 2417296-84-3 |
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| 分子量: | 1001.08 |
| 分子式: | C48H54F2N10O10S |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PROTACBRAF-V600E degrader-1 是一种有效的PROTACBRAF-V600E降解剂，对BRAF和 BRAF-V600E 的Kd分别为 2.4 nM 和 2 nM。PROTACBRAF-V600E degrader-1 通过泛素-蛋白酶体系统 (UPS) 降解 BRAF-V600E。PROTACBRAF-V600E degrader-1 可抑制黑色素瘤细胞的生长。 |
| IC50和靶点: | [{name:"BRAF-V600E:2 nM (Kd)"},{name: "Braf:2.4 nM (Kd)"}] |
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